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Glia maturation factor beta

Oxidative Refolding of Recombinant Human Glia Maturation Factor Beta... [Pg.79]

Glia maturation factor beta (GMF-beta), first detected in this laboratory in 1972 (6-8), is an acidic protein with a molecular mass of 17 kDa present in brains of all vertebrates examined (9,10). GMF-beta promotes the differentiation of glia and neurons, and inhibits the growth of their corresponding tumors (11,12). Although GMF-beta was purified to homogeneity from bovine brain (11), it was not available in sufficient quantity for structural studies. Recently, GMF-beta has been completely sequenced... [Pg.80]

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