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Gestoden

Gestodene Gestodene (54), along with norgestimate and desogestrel, are the progestin components of the third-generation oral contraceptives (see Contraceptives). It may be crystallised from hexane/acetone (81) or ethyl acetate (82), and its crystal stmcture (83) and other spectral data have been reported (84). [Pg.214]

Gestodene has been prepared in several ways (85). The route that provides the highest yield is shown in Eigure 8. Microbial oxidation of (55) with Penicillium raistrickii results in the 15-alcohol (56). Protection of the alcohol as the acetate (57) and protection of the ketone as a dienolether provides (58). In a one-pot procedure (58) is treated with lithium acetyUde and subjected to a hydrolytic work-up to provide gestodene (54) (86). [Pg.214]

Fig. 2. Selected gonane progestogens. (8) desogestrel [54024-22-5] C22H3QO (9) gestodene [60282-87-3] C2 H2g02 (10) norgestimate [35189-28-7] ... Fig. 2. Selected gonane progestogens. (8) desogestrel [54024-22-5] C22H3QO (9) gestodene [60282-87-3] C2 H2g02 (10) norgestimate [35189-28-7] ...
C24H34O3 60919-53-1) see Gestodene 13-ethylgona-5,15-diene-3,17-dione cyclic 3-(2,2-dimetbyl-... [Pg.2380]

C3Hi,ClSi 75-77-4) see Amoxicillin Cefbuperazone cis-Cefprozil Fadrozole Gestodene Indanorex Orlistat Trifluridine... [Pg.2451]

Guengerich FP. Mechanism-based inactivation of human liver microsomal cytochrome P-450 IIIA4 by gestodene. Chem Res Toxicol 1990 3[4] 363 371. [Pg.79]

See other pages where Gestoden is mentioned: [Pg.440]    [Pg.210]    [Pg.211]    [Pg.212]    [Pg.215]    [Pg.222]    [Pg.222]    [Pg.224]    [Pg.229]    [Pg.243]    [Pg.444]    [Pg.115]    [Pg.116]    [Pg.117]    [Pg.85]    [Pg.259]    [Pg.269]    [Pg.239]    [Pg.139]    [Pg.390]    [Pg.391]    [Pg.392]    [Pg.960]    [Pg.960]    [Pg.960]    [Pg.961]    [Pg.961]    [Pg.2280]    [Pg.2366]    [Pg.2383]    [Pg.2385]    [Pg.2395]    [Pg.2395]    [Pg.2395]    [Pg.2406]    [Pg.2407]    [Pg.2429]    [Pg.268]    [Pg.589]    [Pg.620]    [Pg.348]    [Pg.591]    [Pg.623]   
See also in sourсe #XX -- [ Pg.254 ]

See also in sourсe #XX -- [ Pg.252 ]



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