Germ cell specific toxicants, male

Figure 33.5. Transient exposure to a germ cell-specific toxicants produces predicted periods of reduced fertility in males. Males are exposed to a toxicant over a period of one week and then their fertility is monitored by breeding over a period of several weeks. A toxicant that specifically targets epididymal sperm results in almost immediate infertility that recovers over time. A toxicant that specifically targets spermatocytes results in a delay to infertility. A toxicant that specifically targets spermatogonia results in an even greater delay to infertility and may result in permanent infertility.

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