Genus Hernandia alkaloids from

The alkaloids of the Type lib series have oxygenation at C(ll) instead of at C(13), as does vanuatine (255) of the Group Ila series. The only two alkaloids of the Type lib series are vateamine (256X-SpS) and vateamine-2 P-N-oxide (430) from Hernandia peltata. It is apparent that the distribution of both the Type Ila and lib alkaloids is restricted to the genus Hernandia of the family Hemandiaceae. 

Therefore, secondary metabolites such as isoquinoline alkaloids and lignans, from the remaining unstudied species in the genus Hernandia, seem worthy of more extensive chemical and biological investigation. 

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