Genomics The First Link between Sequences and Drug Targets

000 human genes were identified. This increased to 30,261 by 1998. Based on genomic information, the total number of expressed human genes is estimated to be 

000 to 70,000. Recent reports of human genome sequence analysis, however, have prompted scientists to re-assess that estimate [5,6]. 

Additional analysis of DNA sequences in the human genome has revealed that large blocks of human genes are filled with repeated elements, including long interspersed repetitive elements (LINEs) and short interspersed repetitive elements (SINEs). Short interspersed repetitive elements such as Alu sequences are often used as target sequences for DNA fingerprinting. 

The limitations of genomic analysis are being addressed by proteomic analysis. DNA sequence analysis has helped to create protein product libraries and relational databases that hold promise to 

ITABLE 16.3. Some approaches used to study genomic information 

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GENOMICS THE FIRST LINK BETWEEN SEQUENCES AND DRUG TARGETS... 

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