Genome prokaryotes

Genome Management in Prokaryotes Genome Management in Eukaryotes... 

Seven subfamilies of eukaryotic Kir channels, each sharing 60% amino acid identity between individual members within each subfamily and 40% identity between subfamilies, are known [1]. In addition, multiple prokaryotic Kir channels (Kirbacl.1-9) are now being identified in bacterial genomes. We will focus on the eukaryotic channels. 

Studnicka, G. M. (1987). Nucleotide sequence homologies in control regions of prokaryotic genomes. Gene 58, 45-57. 

A more detailed breakdown of the fold abundance by individual genomes shows the same trends, as well as a number of unique features (Fig. 6, see color insert). The latter include, for example, the marked overrepresentation of Rossmann-fold domains in Mycobacterium, flavo-doxins in Synechocystis and methyltransferases in Helicobacter. Furthermore, the differences in fold distribution between the multicellular eukaryote Caenorhabditis elegans and the unicellular yeast become readily apparent. In the nematode, the protein kinases are the most common fold, with the P-loops relegated to the second position in contrast, the yeast distribution is more similar to that seen in prokaryotes (Fig. 6). 

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