Genetic code colinearity

The genetic code During translation, the sequence of an mRNA molecule is read from its 5 end is a triplet code by ribosomes which then synthesize an appropriate polypeptide. Both in prokaryotes and eukaryotes, the DNA sequence of a single gene is colinear with the amino acid sequence of the polypeptide it encodes. In other words, the nucleotide sequence of the coding DNA strand, 5 to 3, specifies in exactly the same order the amino acid sequence of the encoded polypeptide, N-terminal... 

Sense strand. The strand of DNA during transcription which is not transcribed into mRNA. This results from its position as colinear, as opposed to complementary, for the RNA sequence. It makes sense with the genetic code. 

The central dogma of molecular biology is that information is transferred from DNA to RNA to proteins. The proteins (which include the enzymes and structural components of cells) are directly responsible for most cellular activities and functions. The information needed for all functions of all organisms is stored in the genomic DNA sequence, which contains discrete units defined as genes. Each gene encodes a protein whose function and activity are determined by its primary sequence. The discovery of colinearity of the DNA nucleotide sequence and the amino acid sequence of the encoded polypeptide in prokaryotes and their viruses led to the discovery of the genetic code... 

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