General Pharmacology of Morphine

The administration of morphine is followed by a series of complex events. Analgesia, euphoria, addiction, and respiratory depression are stressed in the literature, but if morphine had only its effect on carbohydrate metabolism it would rank wdth insulin and phloridzin in interest if it had only its effect on smooth muscle it would rank with pilocarpine and physostigmine and if it had only its effect on gastric secretion and salivation it wmuld rank with histamine. But consideration of some effects is lost in the importance of analgesia and only possible counter indications to its use as an analgesic remain continuously on the experimental horizon. 

The majority of the effects seen in man and other animals after the ad- 

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