General-acid-base catalysis kinetically equivalent mechanism

As with intermoleculariy general-acid and general-base catalysed reactions, it is frequently difficult to distinguish between kinetically equivalent mechanisms and eliminate all but one. Mechanisms which involve intramolecular nucleophilic catalysis are often kinetically equivalent to those which involve intramolecular general-acid or base catalysis. As these do not involve a proton transfer they will not be discussed in this chapter unless the evidence is fairly evenly balanced between them and the latter. 

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