Gene expression binding protein

Control of gene expression through proteins like cAMP response element binding (CREB) protein (requires hours) Control of gene expression (requires hours)... 

Finally, the rate of initiation of RNA synthesis can be controlled by auxiliary regulatory proteins that affect the rate of formation of the polymerase-promoter complex. According to their positive or negative action on gene expression, regulatory proteins are known as activators or repressors, respectively. Activators augment polymerase binding to the promoter, whereas repressors have the opposite effect. 

Some ligands do not interact principally with cell surface receptors, but diffuse into cells and bind to intracellular receptors in the cytoplasm. For example, ligand binding to cytoplasmic steroid receptors initiates a process that is not well understood but that involves the movement of steroid-bound receptor into the cell nucleus, where the receptor molecule interacts with genomic material, resulting in alterations in gene expression and protein synthesis. 

BLIMPl a protein that acts as a repressor of beta-interferon gene expression. The protein binds specifically to the PRDI (positive regulatory domain I element) of the 3-IFN gene promoter. Transcription of this gene increases upon virus induction. 

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