Gelling agents chitosan

Calcium chloride solution (+) Cross-linking Agent + Chitosan solution (+) PEC Agent lonotropically gelled and chitosan-reinforced hydrogel beads... 

Chitosan is used as an emulsifier (for margarine) and an emulsion stabiliser (it is added to hamburgers, ice creams and cheeses), thickener (viscosity increases), foam stabiliser, gelling agent, clarification agent for fruit juices and also in the pharmaceutical industry and in cosmetics. 

The cohesion is the ability of the paste to maintain its shape upon contact with body liquid. Washout of the cement may result in inflammatory reactions at the defect site (Ishikawa 2008). Small particle sizes, low L/P ratios or addition of gelling agents (0.2-2% sodium alginate, 0.4-1.5% chitosan, 2-4% hydroxypropylmethyl or carboxymethyl cellulose) can be used to prevent disintegration of the paste (Takechi et al. 1996 Cherng et al. 1997 Ishikawa et al. 1997). 

Sakloetsakun D, Hombach JM, Bemkop-Schnurch A (2009) In situ gelling properties of chitosan-thioglycolic acid conjugate in the presence of oxidizing agents. Biomaterials 30 6151-6157... 

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