Gastric juice mammal

Concerning histamine, ponderous volmnes have been written. It invariably can be demonstrated in the tissues (skin, leucocytes) of mammals, but exists there in a bound and inactive form. Its chief effects are dilation of the blood capillaries, elevation of the secretion of gastric juice, and phenomena resembling anaphylactic shock. It is suspected that histamine controls local blood circulation in the normal organism. Histamine also plays a role in the production of allergic reactions. Consequently, substances that inhibit the physiological effects of histamine (antihistamines) are used therapeutically. 

Pilocarpine increases the secretion of sweat, saliva, tears, and mucus, and of the gastric and pancreatic juices. It causes contraction of the pupil of the eye, and of most smooth muscle, though not that of the blood vessels. In mammals, it causes a transient slowing of the heart, followed by an acceleration and an increase in blood pressure. 

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