Ganglioside Unsaturated fatty acid

Unsaturated PE does not form stable liposomes under physiological conditions but forms stable ones on the addition of a second component to PE. Several stabilizers for PE bilayers examined include fatty acids [93,94], detergents [105], gangliosides [106,107], diacylphospholipids [108,109], ly-solipids [105,109], haptenated lipids [110], diacylsuccinylglycerols [102, 111], cholesterol [112], cholesterol derivatives [97], membrane glycoproteins [113,114], palmitylated amino acids [89], palmitylated enzyme [115] and palmitylated antibody [116]. Many lipids stabilize PE bilayers at 20 mol% or higher [108]. 

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