Galectins genes

Table 1. Mammalian galectin and candidate genes. Sequencing of cosmids indicated with an asterisk is still in progress, so position numbering for the deduced exon boundaries may change with each update.

Table 2. Non-maimnalian galectin and candidate genes. Asterisks mark candidate galectins (not yet shown to bind galactosides). Not included are numerous candidate nematode galectins (C. elegans and others). ... 

Galectin-3 mRNA was detected in mouse eosinophils (27). Disruption of galectin-3 gene in mice has been shown to reduce macrophage-mediated peritoneal inflammation and seems to be involved in chemoattraction of monocytes and macrophages (32). 

Hsu DK, Yang RY, Pan Z, Yu L, Salomon DR, Fung-Leung WP, Liu FT. Targeted disruption of the galectin-3 gene results in attenuated peritoneal inflammatory responses. Am J Pathol 2000 156 1073-1083. 

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