Galactitol 6- deoxy

L-Fucitol (l-Fuc-oI) or 1-deoxy-D-galactitol not 6-deoxy-L-galactitol (cf. 2-Carb-2.2.3.1)... 

Support for this result was obtained from the taste of 1,5-anhydrohexitols, which, only for purposes of comparison, can be regarded as 1-deoxyal-dopyranoses. 1,5-Anhydro-D-glucitol (that is, the incorrectly named 1-deoxy-D-glucopyranose ) (14), 1,5-anhydro-D-mannitol ( 1-deoxy-D-mannopyranose or 2-deoxy-D-fructopyranose ) (15), and 1,5-anhydro-D-galactitol ( l-deoxy-o-galactopyranose ) (16) are all purely sweet, without any trace of bitterness. Furthermore, the complete absence of bitterness of 1,5-anhydromannitol (16) clearly indicates that the anomeric... 

On treatment with concentrated halogen acids, certain hexitols yield 1,6-dideoxy-l,6-dihalo compounds. The structure of the compound so obtained from galactitol, first reported by Bouchardat,404 was later verified by synthesis.405 Allitol is transformed406 into 1,4-anhydro-6-chloro-6-deoxy-DL-allitol and l,4-anhydro-5,6-dichloro-5,6-dideoxy-DL-talitol on treatment with fuming hydrochloric acid at 100°. 

Scheme 20.—Potential, Photochemical-Reaction Pathways for Reaction of 1-Deoxy-l-(ethysulfinyl)-D-galactitol (47).

Deoxy-l-fluoro-L-glycerol (18) has been prepared by, among other methods, the treatment of 3,4-0-benzylidene-2,5-0-methylene-l,6-di-O-p-tolylsulfonyl-D-mannitol107 (17) with tetrabutylammonium fluoride in acetonitrile, followed by removal of the benzylidene group, periodate oxidation, reduction with borohydride, and hydrolysis. 1,6-Dideoxy-l,6-difluorogalactitol108 was obtained by treatment of 2,3 4,5-di-0-isopropylidene-l,6-di-0-(methylsulfonyl)galactitol with tetra-... 

Linear [ ]-pol3turethane derived from 1-deoxy-l-isocyanate-2,3 4,5-di-(9-iso-propylidene-D-galactitol (prepared from 48) in the presence of TEA or Zr(acac)4, as well as its corresponding polyhydroxy derivative obtained by hydrolysis of the acetal protecting group, have been prepared [117]. They are semicrystalline materials that exhibit high melting temperatures and thermal stability up to 230°C. 

Proton coupling-constants were determined65 for the tri-O-acetyl derivatives of bis(ethylsulfonyl)-a-D-lyxopyranosylmethane [2,6-anhydro-l,l-bis(ethylsulfonyl)-l-deoxy-D-galactitol] (29) and bis(eth-... 

Borohydride reduction of 2-acetamido-2-deoxy-D-galactose affords 2-acetamido-2-deoxy-D-galactitol,219 whereas oxidation of the benzyl 2-(N-benzyloxycarbonyl)amino or-D-glycoside with oxygen in the presence of platinum oxide, followed by hydrogenolysis of the blocking groups, yields... 

---