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GABAergic agonists

Thus, the two GABAergic agonists, isoguvacine and THIP (Figure 15.21), have similar pharmacological properties... [Pg.303]

Arylpropionic analgesic and anti-inflammatory drugs 6. GABAergic agonists... [Pg.346]

The term non-classical isosterism is often used, interchangeably with the term bioisosterism, for example, when one has to deal with isosteres that do not possess the same number of atoms, but which have in common some key parameter of importance for the activity in a given series. Thus, the two GABAergic agonists isoguvacine and THIP (Fig. 13.3) possess similar pharmacological properties to GABA itself. The key parameters in these compounds are... [Pg.191]

Kelly, P. A. T., and McCulloch, J., 1982a, The effects of the putative GABAergic agonists, muscimol and TRIP, upon local cerebral glucose utilizations./. Neurochem. 39 613-624. [Pg.403]

A medication that causes induction of sleep. The majority of currently available hypnotics (for example benzodiazepine receptor agonists) act via potentiating the brain s inhibitory GABAergic systems, in turn reducing the activity of arousal (i.e. wake promoting) neurotransmitter systems. [Pg.608]

See other pages where GABAergic agonists is mentioned: [Pg.466]    [Pg.63]    [Pg.295]    [Pg.348]    [Pg.348]    [Pg.379]    [Pg.380]    [Pg.382]    [Pg.384]    [Pg.396]    [Pg.466]    [Pg.63]    [Pg.295]    [Pg.348]    [Pg.348]    [Pg.379]    [Pg.380]    [Pg.382]    [Pg.384]    [Pg.396]    [Pg.537]    [Pg.443]    [Pg.912]    [Pg.1137]    [Pg.11]    [Pg.11]    [Pg.246]    [Pg.237]    [Pg.488]    [Pg.268]    [Pg.102]    [Pg.148]    [Pg.10]    [Pg.89]    [Pg.263]    [Pg.265]    [Pg.347]    [Pg.350]    [Pg.351]    [Pg.374]    [Pg.443]    [Pg.451]    [Pg.27]    [Pg.95]    [Pg.470]    [Pg.244]    [Pg.283]    [Pg.296]    [Pg.297]    [Pg.122]    [Pg.35]    [Pg.35]   
See also in sourсe #XX -- [ Pg.303 , Pg.306 , Pg.346 , Pg.348 ]

See also in sourсe #XX -- [ Pg.303 , Pg.306 , Pg.346 , Pg.348 ]



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GABAergic

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