Furans, nitro-, synthesis

Thieno[3,4-d][l,3]dithiol-2-one, 1-nitro-synthesis, 6, 1013 Thieno[3,4-c]furan, 4,6-dichloro-synthesis, 6, 1013 Thieno[3,4-c]furan, tetraphenyl-formation, 4, 1060 synthesis, 4, 1060 UV spectra, 4, 1044 Thieno[3,2-6]furans structure, 4, 1039 synthesis, 6, 1020 Thieno[3,4-c]furans... 

Furan, 2-(p-hydroxyphenyI)-2,5-dihydro-synthesis, 4, 677 Furan, 3-hydroxytriphenyl-tautomerism, aromaticity and, 4, 595 Furan, iodo-synthesis, 4, 712 Furan, 2-iodo-Grignard reagents, 4, 79 Furan, 5-iodo-2-nitro-synthesis, 4, 711 Furan, 2-isopropyl-cycloaddition reactions with ff, ,a, ff -tetrabromoacetone, 1, 418 Furan, 2-lithio-5-methyl-synthesis, 1, 419 Furan, 2-mercapto-tautomerism, 4, 38 Furan, 3-mercapto-tautomerism, 4, 38 Furan, methoxy-planarity, 4, 544 synthesis, 4, 664 Furan, 2-methoxy-synthesis, 4, 648 Furan, 3-methoxy-Diels-Alder reaction, 1, 416 synthesis, 4, 649... 

Benzo[b]furan, 2-nitro-reduction, 4, 74, 647 Benzo[b]furan, 5-nitro-mass spectrometry, 4, 583 Benzo[b]furan, 2-(4-nitrophenyl)-properties, 4, 708 Benzo[b]furan, 2-phenyl-bromination, 4, 605 chloromethylation, 4, 607 nitration, 4, 604 photochemical reactions, 4, 636 properties, 4, 697 Benzo[b]furan, 3-phenyl-synthesis, 4, 697... 

Furan, 2,5-bis(trimethylsilyloxy)-cycloaddition reactions, 4, 625 Diels-Alder reactions, 4, 77 synthesis, 1, 417 Furan, bromo-dipole moments, 4, 553 Furan, 2-bromo-electron diffraction, 4, 537 reactions, 4, 78 synthesis, 4, 604 Furan, 3-bromo-electron diffraction, 4, 537 Furan, 2-bromomethyl-5-nitro-reactions... 

Furan, 2,3-dihydro-5-methyl-polymers, 1, 276 Furan, 2,3-dihydro-3-methylene- H NMR, 4, 577 Furan, 2,5-dihydro-2-methylene- H NMR, 4, 577 tautomerism aromaticity and, 4, 595 Furan, 2,5-dihydro-2-nitro-structure, 4, 550 Furan, 2,3-dihydroxy-tautomerism, 4, 37 Furan, 2,4-dihydroxy-tautomerism, 4, 37 Furan, 3,4-dihydroxy-tautomerism, 4, 37 Furan, 2,5-diiodo-nitration, 4, 602 synthesis, 4, 712 Furan, 3,4-diiodo-reactions, 4, 650 Furan, 2,3-dimethoxy-synthesis, 4, 625, 648 Furan, 2,5-dimethoxy-synthesis, 4, 648 Furan, 3,4-dimethoxy-cycloaddition reactions, 4, 64, 625 lithiation, 4, 651 reactions... 

Furan-2-carbaldehyde, 5-methyl-synthesis, 4, 658 Furan-2-carbaldehyde, 5-nitro-as chemotherapeutic agent, 1, 179... 

Yosikoshi reported the synthesis of furan derivatives by the reaction of 1,3-diketones with nitroalkenes, in which the Michael addition of the anions of 1,3-diketones and the subsequent intramolecular displacement of the nitro group by enolate oxygen are involved as key steps (Eq. 7.40).42... 

Sequential Michael additions are versatile methods for the construction of cyclic compounds. Although a variety of these reactions have been developed, the use of alcohols as nucleophiles for the Michael addition to nitroalkenes has been little studied. Recently, Ikeda and coworkers have reported an elegant synthesis of octahydrobenzo[b]furans via the sequential Michael addition of 1-nitro-cyclohexene with methyl 4-hydroxy-2-butynoate in the presence of t-BuOK followed by radical denitration (Eq. 7.74).94... 

In contrast, triphenylphosphine displaces bromide smoothly and the Wittig reaction then possible provides the recommended synthesis of 2-nitro-5-vinylfuran as sketched in scheme 35, B.192 Halomethylfurans and cyanide ion give nuclear substitution, as has long been known (Scheme 35, C). Nuclear substitutions occur for 2,5-bis(chloromethyl)furan,193 but are less... 

Andreae, S. and Seeboth, H., Synthesis of 2-furyl- and 5-nitro-2-furyl-sub-stitued vinylphosphonic acids, Collect. Led. Int. Symp. Furan Chem., 3rd Slovak Tech. Univ., Fac. Chem. Technol., Bratislava, Czechoslovakia, 1979, p. 117. 

Synthesis and properties of unsaturated nitro compounds of the furan series 93UK184. 

Both 2- and 3-nitrofurans with additional substituents on the available positions of the furan ring have been synthesized by cyclization procedures. The nitro-containing reagents are of type 1 or 2. No type 3 reagent seems to have been used for the synthesis of nitrofurans or condensed nitrofurans. 

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