2 -furanone, 3-Ethyl dihydro-4- 1- methyl

In the 3-phenyl-2(3 )-benzofuranone series, we find a long-known spasmolytic compound, 3-(2-diethylamino)ethyl-3-phenyl-2(3fI)-benzo-furanone (Amolanone), which also has analgesic properties. A novel compound, 2-(l-succinyloxy)ethyl-3-methyl-5-(2-oxo-2,5-dihydro-4-furyl)benzofuran or Benfurodil (25) (clinical name Eudilat), is a vasodilator and cardiotonic. 

H)-Furanone, dihydro-5-(3-ethyl-4-methyl-1-pentenyl)-3-hydroxy-5-methyl- 4249 ... 

Ethyl-4-methyl-l-pentenyI)-4,5-dihydro-3-hydroxy-5-methyl-2(3 furanone, 9Ci... 

Ethyl-3-methyl-2,4,6-nonatriene, E-30154 5-(3-Ethyl-4-methyl-1 -pentenyl )-4,5-dihydro-3-hydroxy-5-methyl-2(3//)furanone, E-30155... 

Lithio-2-(2,2-dimethoxyethyl)-l,3 dithian, when it reacted with ketcmes and epoxides, led to intermediates which were converted in somewhat low yield into 3-furanones and dihydro-y-pyrones, respectively. " 2-Methyl-2-lithio-dithian reacted efficiently with spiro-epoxide groups at positions 3 and 17 in steroids. The products obtained in this manner were further elaborated for example, 3a-ethyl-30-hydroxy-5a-cholestane, " 3-acetonyl-A -androstane, and both isomers of 17-acetonyltestosterone " were prepared. The carbon skeleton, including the S-lactone ring, of pestalotin... 

Figure 5.2.10. Cellulose pyrolysate obtained at 59CP C by Py-GC/MS. The separation was done on a Carbowax type column. 1 CO2, 2 acetaldehyde, 3 acetone, 4 2-butanone, 5 2,3-butandione, 6 toluene, 7 water, 8 cyclopentanone, 9 methylfuran, 10 3-hydroxy-2-butanone, 11 hydroxypropanone, 12 cyclopent-1-en-2-one, 13 2-methylcyclopentenone, 14 acetic acid, 15 acetic acid anhydride, 16 furancarboxaldehyde, 17 methylcyclopentenone, 18 dimethylcyclopentenone, 19 5-methylfurancarboxaldehyde, 20 2,3-dihydro-2-furanone, 21 furan-2-methanol, 22 3-methylfuran-2-one, 23 2(5H)-furanone, 24 hydroxycyclopentenone, 25 3,5-dimethylcyclopentan-1,2-dione, 26 2-hydroxy-3-methyl-2-cyclopenten-1-one, 27 2-hydroxy-3-ethyl-2-cyclopenten-1-one, 28 2,3-dimethyl-2-cyclopenten-1-one, 29 phenol, 30 dimethylphenol, 31 3 thyl-2,4(3H,5H)-furandione, 32 3-butenoic acid, 33 1,4 3,6-dianhydro-a-D-glucopyranose, 34 5-(hydroxymethyl)-furfural.

Figure 5.2.11. Cellulose pyrolysate obtained at 59(P C and separated on a methyl silicone with 5% phenyl silicone type column. 1 acetic anhydride, 2 pentanal, 3 2-hydroxybutanedialdehyde, 4 1,4-dioxadiene, 5 tetrahydro-2-furanmethanol, 6 2-(hydroxymethyl)-furan, 7 3-methyl-2-hexanone, 8 2-methoxy-2,3-dihydrofuran, 9 2(5H)-furanone, 10 1-acetyloxypropan-2-one, 11 hydroxycyclopentenone, 12 5-methylfurfural, 13 2,3-dihydro-5-methylfuran-2-one, 14 1-cyclopentylethanone, 15 2-hydroxy-3-methyl-2-cyclopenten-1-one, 16 3,5-dimethylcyclopentan-1,2-dione, 17 unknown, 18 3-ethyl-2,4(3H,5H)-furandione, 19 6-methyl-1,4-dioxaspiro[2,4]heptan-5-one, 20 1-hydroxy-3,6-dioxabicyclo[3.2.1]octan-2-one, 21 1,4 3,6-dianhydro-a-D-glucopyranose, 22 5-(hydroxymethyl)-furfural, 23 4-cyclopenten-1,2,3-triol, 24 5-ethyl-3-hydroxy-4-methyl-tetrahydrofuran-2-one, 25 levoglucosan, 26 1,6-anhydro-p-D-glucofuranose.

G.13) 2(5/f)-Furanone, 5-ethyl-3-hydroxy-4-methyl-, 2-hydroxy-3-methylhex-2-eno-4-lactone, 5-ethyl-2,5-dihydro-3-hydroxy-4-methylfuran-2-one, 4-ethyl-2-hydroxy-3-methyl-2-buten-4-olide, 2,4-dihydroxy-3-methyl-2-hexenoic acid, 7-lactone, a-hydroxy-p-methyl-Aa,p-7-hexenolactone, abhexone 698-10-2] FEMA 3153 ( )- 1144810-13-9] (/ )- 144831-60-7J (5)- 14483l-61-8]... 

H)-Furanone, dihydro-6-(4-hyd oxy-4-methyl-7-(1-methylethyl)-10-oxo-1,5-u decadie yl]-S-m ethyl- stereoisomer 4249, 4947 ... 

Piocarpine ((35)-ci5-3-ethyl-4-( 1 -methyl-5-imidaz-olylmethyl)-dihydro-2(3//)-furanone]. 

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