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From atom fragments

This type of cyclization is important only for the formation of cinnolines. In all cases, the starting compounds have an ortho amino group, which upon diazotization undergoes ring closure with the other functionality, most frequently with a multiple bond. [Pg.43]

Generally, it was stated that the most significant correlation was found between the values of Pmw and po lipophilic parameters and logPRowwin calculated from atom/fragmental contribution values. MlogP correlates with the above-mentioned lipophilic parameters slightly worse than logPRowwin does (r > 0.90). It was found that... [Pg.180]

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