Fraser-Reid s laboratories

Prior to this study there were two precedents in the literature of cycloaddition reaction of carbohydrate derived dienes where the diene moiety was incorporated into the ring. The first example came from Fraser-Reid s laboratories (30) on a furanoid derived diene 38 in Figure 12, and shortly after Giuliano and Buzby reported on a pyranose diene 39 (17), Of special interest to us was that in both reports just one single adduct was... 

---