Frans polymer bound

The first example of the use of a polymer-bound cinchona alkaloid in the AD was described in 1990 by Sharpless [48,49], The polymer was readily obtained by radical co-polymerization of 9-(p-chlorobenzoyl)quinidine acrylate with acrylonitrile. First applications in dihydroxylations of frans-stilbene using NMO as co-oxidant yielded products with enantioselectivities in the range of 85 -93 % ee. It is interesting that a repetitive use of the polymer was possible without great loss of reactivity, indicating that the metal was retained in the polymeric array. 

---