Framework for EU Risk Assessment

The risk assessment procedures for the CSR will certainly be based on the current procedures, although it would be useful if the ECA software simplified them to help registrants. 

Exposure to a substance can potentially occur during each stage of the life cycle of the substance in the EU, from production to ultimate disposal or recovery (Table 19). At each of the stages of the lifecycle, the exposure to the various environmental compartments and human populations has to be assessed. 

Assessment of effects a) Hazard identification (intrinsic hazardous properties of the substance) b) Elucidation of the dose (concentration) versus response (effects) characteristics  

Exposure assessment a) For the human population, workers, consumers and indirect exposure via the environment b) For the different environment compartments likely to be exposed to the substances water, sediment, soil, and air  

Risk characterisation Comparison of information on hazardous properties and effective dose levels/ concentrations with exposure levels in order to characterise the degree of risk posed by the substance to human health or to the environment  

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