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Formylglycinamidine ribonucleotide

The product of this reaction, formylglycinamidine ribonucleotide, cyclizes to form the five-membered imidazole ring found in purines. Although this cyclization is likely to be favorable thermodynamically, a molecule of ATP is consumed to ensure irreversibility. The familiar pattern is repeated a phosphoryl group from the ATP molecule activates the carbonyl group and is displaced by the nitrogen atom attached to the ribose molecule. Cyclization is thus an intramolecular reaction in which the nucleophile and phosphate-activated carbon atom are present within the same molecule. [Pg.1039]

OXALYL-CoA DECARBOXYLASE N-Formylglutamate transformylase, GLUTAMATE FORMYLTRANSFERASE FORMYLGLYCINAMIDE RIBONUCLEOTIDE AMIDOTRANSFERASE FORMYLGLYCINAMIDINE SYNTHETASE... [Pg.744]

See other pages where Formylglycinamidine ribonucleotide is mentioned: [Pg.295]    [Pg.865]    [Pg.88]    [Pg.83]    [Pg.88]    [Pg.865]    [Pg.598]    [Pg.284]    [Pg.391]    [Pg.391]    [Pg.404]    [Pg.405]    [Pg.418]    [Pg.720]    [Pg.295]    [Pg.865]    [Pg.88]    [Pg.83]    [Pg.88]    [Pg.865]    [Pg.598]    [Pg.284]    [Pg.391]    [Pg.391]    [Pg.404]    [Pg.405]    [Pg.418]    [Pg.720]   
See also in sourсe #XX -- [ Pg.308 ]



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Ribonucleotides

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