Formation of Surfactants with Aromatic Compounds and their Pharmaceutical Applications

Yuji Ohashi, Keiju Sawada and Nahoko limura 

Surface-active agents (surfactants) are a series of compounds consisting of hydrophobic and hydrophilic moieties. An aqueous solution containing a surfactant forms micelles above a critical concentration, which is called the critical micelle concentration (cmc). The value of the cmc is approximately (1 M = 1 moldm ) in the case of 

Although a number of methods have been proposed to determine the cmc of surfactants, such as electrical conductance [4, 5], transference number [6, 7], dye absorption [8-10], solubilization [11-15], surface tension [16, 17], partial molar volume [18, 19], 

Organic Crystal Engineering Frontiers in Crystal Engineering Edited by Edward R.T. Tiekink, Jagadese Vittal and Michael Zaworotko 2010, John Wiley Sons, Ltd 

Micelles with platelet or rod-like shapes were obtained in supersaturated aqueous solution containing a surfactant and an aromahc compound. In particular, chiral surfactants are known to produce enantiomeric precipitahon, while most of the others give symmetric micelles [45-47]. 

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Complex Formation of Surfactants with Aromatic Compounds and their Pharmaceutical Applications... 

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