Forensic toxicology chemical compound identification

Figure 16.2. Schematic presentation of procedure for identification of chemical compounds and other traces for forensic toxicology or criminalistic purposes [4],...

Sensitive identification, screening, and quantitation of 18 compounds of interest were achieved in chromatographic separation in only 4.40 min. Accurate and reproducible results were obtained by using five different and carefully selected deuterated analogs on the basis of the chemical properties of the target analytes. The extraction efficiencies ranged from 74.3% to 105.7% and the limits of quantitation (LOQ) from 1 to 100 ng/ml. The method was fully validated and is applicable for sensitive, reliable, and quantitative determination of benzodiazepines, zaleplon, and zopi-clone, for example, in clinical and forensic toxicology [9]. 

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