Food suppression

Numerous substances are produced by plants, animals, and microorganisms to protect themselves from predators, locate sources of food, suppress or avoid... 

The cytokine leptin is secreted by adipocytes (fat cells) in proportion to the size of the adipose dq>ot and circulates via the bloodstream to the brain, where it ultimately affects feeding behavior, endocrine systems including reproductive function and, at least in rodents, energy expenditure. The major effect of Lqrtin is on the hy-pothalamous, where it suppresses appetite and hence food intake. Leptin exerts its effects via binding to the leptin receptor in the brain (specifically in the hypothalamus), which activates the JAK-STAT Pathway. 

TSUTSUML K, KAWAUCHI Y, KONDO Y, INOUE Y, KOSHITANI O, KOHRL H (2000) Water extract of defatted rice bran suppresses visceral fat accumulation in rats. JAgri Food Chem, 48(5) 1653-6. 

Hu, C. et al., Black rice (Oryza sativa L. indica) pigmented fraction suppresses both reactive oxygen species and nitric oxide in chemical and biological model systems, J. Agric. Food Chem., 51, 5271, 2003. 

Similarly to the methods used to characterize natural chlorophylls, RP-HPLC has been chosen by several authors to identify the individual components in Cn chlorophyllin preparations and in foods. The same ODS columns, mobile phase and ion pairing or ion suppressing techniques coupled to online photodiode UV-Vis and/or fluorescence detectors have been used. ° ... 

Physico-chemical instrumental analysis nowadays has greatly suppressed such chemical handwork. An internet website disseminates methods of analysis and supporting spectroscopic information on monomers and additives used for food contact materials (principally packaging). 

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