Folding and aggregation

Irback, A., Mohanty, S. PROFASI a Monte Carlo simulation package for protein folding and aggregation. J. Comput. Chem. 2006, 27,1548-55. 

Yoshikawa, Y., Emi, N., Kanbe, T., Yoshikawa, K. and Saito, H. (1996d) Folding and aggregation of DNA chains induced by complexation with lipospermine formation of a nucleosome-like structure and network assembly. FEBSLett., 396, 71-76. 

This case is particularly relevant in regard to the formation of inclusion bodies (see Section 17.6 below) as overexpression of a target protein is a mode of obtaining the protein. With the assumption that folding and aggregation behave as in case 1, and nascent protein is expressed with a zerofh-order rate constant k0 with respect to the... 

T. Kiefhaber, R. Rudolph, H. H. Kohler, and J. Buchner, Protein aggregation in vitro and in vivo a quantitative model of the kinetic competition between folding and aggregation, Bio/Technology 1991, 9, 825-829. 

Zahn R (2003) The octapeptide repeats in mammalian prion protein constitute a pH-dependent folding and aggregation site. J Mol Biol 334 477 -88... 

Winklhofer KF, Heske J, Heller U, Reintjes A, Muranyi W, Moarefi I, Tatzelt J (2003) Determinants of the in vivo folding of the prion protein - a bipartite function of helix 1 in folding and aggregation. J Biol Chem 278 14961... 

In this section, the folding and the presently known conformational states of disufide-intact recombinant prion proteins are discussed. Section 111 deals with biophysical studies on folding and aggregation of reduced... 

Chiti F, Taddei N, Baroni F, Capanni C, Stefani M, Ramponi G et al (2002) Kinetic partitioning of protein folding and aggregation. Nat Struct Biol 9(2) 137-143... 

Chen, Y.R. and Glabe, C.G. 2006. Distinct early folding and aggregation properties of Alzheimer amyloid-P peptides AP40 and AP42 Stable trimer or tetramer formation by AP42. J. Biol. Chem. 281 24414-24422... 

Bereau, T, 8c Deserno, M. (2009). Generic coarse-grained model for protein folding and aggregation. Journal of Chemical Physics, 130, 235106. 

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