Focal complexes

Rho family proteins serve as important mediators for integrin outside-in signaling. Integrin clustering and focal complex... 

Nobes CD, Hall A. Rho, rac, and cdc42 GTPases regulate the assembly of multimolecular focal complexes associated with actin stress fibers, lamellipodia, and filopodia. Cell 1995 81 53-62. Nobes CD, Hall A. Rho, rac and cdc42 GTPases regulators of actin structures, cell adhesion and motility. Biochem. Soc. Trans. 1995 23 456-459. 

Seizures are the initial symptom in 16%-53% of patients, with a mean of 34% (Mast et al. 1995). In the majority of cases, seizures are focal or focal complex (Osipov et al. 1997). Grand mal seizures are encountered in 27%-35% of cases (Osipov et al. 1997). 

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