FLZ:p-CD inclusion complex

Determination of the FLZ.-p-CD Inclusion Complex Stoichiometry by Continuous Variation Method (Job s Plot)... 

Figure 2. Jobs plot (continuous variation method) of FLZ p-CD inclusion complex showing 1 1 stoichiometry.

In this procedure, the plot of chemical shift changes (A6) for the P-CD protons against [FLZ] in the form of [FLZ]/A6obs versus [FLZ] (referred to as y-recip-rocal plot) should be linear for 1 1 inclusion complex. The slope of the plot thus equals to 1/A5max and the intercept with the vertical axis to A5max/Ka, allowing the estimation of association constant (Ka). A typical Scott s plot for FLZ P-CD inclusion complex is shown in figure 3 and the association constant (Ka) was calculated to be 68.7 M-1. 

Figure 3. A typical Scott s plot for FLZ p-CD inclusion complex showing overall association constant (K ) S8.7M-1.

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