Flurogestone acetate

Molecular formula C23H31FO5 Molecular weight 406.49 CAS Registry No 2529-45-5 Merck Index 13,4226 

Column 300 x 3.9 10 n-m n-Bondapak CIS Mobile phase MeOHrwater 50 50 Flow rate 2 Detector UV 254 

Kabadi, M.B. Valia, K.H. Chien, Y.W. Intravaginal controlled administration of flurogestone acetate I development of a stability-indicating liquid chromatographic method and stability kinetics of flurogestone acetate, J.Pharm.Sci., 1984, 73, 1461-1464. 

Mobile phase Gradient. A B from 45 55 to 100 0 over 12 min. A was MeCN water formic acid 10 90 0.5. B was MeCN water formic acid 90 10 0.5. 

Detector MS, Micromass Quattro Ultima, positive electrospray, capillary 2.5 kV, cone 40 V, source 120°, cone gas 189 L/h, desolvation gas 652 L/h, m/z 407.2-267.4-225.4 

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Kabadi, M. Chien, Y. Intravaginal controlled administration of flurogestone acetate III. Drug Dev. Ind. Pharm. 1985,11, 1271-1312. 

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