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Fluorous small-molecule microarrays

Figure 16.2 Fluorous small-molecule microarrays. Small-molecule histone deacetylase (FiDAC) binders are noncovalently immobilized onto a glass slide coated with fluorocarbon compounds. An antibody labeled with a fluorescent dye recognizes HDAC proteins. See color plate 16.2. Figure 16.2 Fluorous small-molecule microarrays. Small-molecule histone deacetylase (FiDAC) binders are noncovalently immobilized onto a glass slide coated with fluorocarbon compounds. An antibody labeled with a fluorescent dye recognizes HDAC proteins. See color plate 16.2.
Vegas, A. J., Brander, J. E., Tang, W., et al. (2007) Fluorous-based small-molecule microarrays for the discovery of histone deacetylase inhibitors. Angewandte Chemie International Edition, 46(42), 7960-7964. [Pg.440]

Nicholson, R. L., Ladlow, M. L., Spring, D. R. (2007). Fluorous tagged small molecule microarrays. Chem. Commun., 3906-3908. [Pg.79]


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