Fluorophores encapsulation into liposomes

Fig. 2. Liposome structure (A) Biorecognition elements can be covalently conjugated to or inserted into lipid bilayers through hydrophobic interactions (not to scale.) (B) The large internal volume of unilamellar vesicles can encapsulate hundreds of thousands of hydrophilic signaling molecules and provide for their stability. (C) Surfactant introduction can provide for instantaneous signal enhancement through release of encapsulants. Fluorophores encapsulated within liposomes at high concentrations undergo self-quenching, which is overcome upon release into the surrounding medium.

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