3- fluorophenyl methyl

Chemical Name 1-[(4-Fluorophenyl)methyl] -N-[1 -[2-(4-methoxyphenyl)ethyl] -4-piperi-dinyl] -1 H-benzimidazol-2-amine... 

Chemical Name 1 -[Bis(4-fluorophenyl)methyl] -4(3-phenyl-2-propenyl)piperazine Common Name —... 

CN 6-[4-[bis(4-fluorophenyl)methyl]-l-piperazinyl]-A(,(V -di-2-propenyl-l,3,5-triazine-2,4-diamine... 

CN [2-amino-6-[[(4-fluorophenyl)methyl]amino]-3-pyridinyl]carbamic acid ethyl ester... 

CN 4-Amino-5-chloro-2-ethoxy-A-[[4-[(4-fluorophenyl)methyl]-2-morpholinyl]methyl]benzamide citrate... 

N l(4-fluorophenyl)melhy ]-3-nitro-2,6-pyridinediamine (Cj2HjiFN402 33400-49-6) see Flupirtine 4-(4 fluorophenyl) a methyl-l-piperazinepropanamine (C14H22FN3 27367-89-1) see Niaprazine l-[(4 fluorophenyl)methyl]- -4-piperidinyMH-benz-imidazol-2>amine... 

Fluorophenyl methyl ketone, AMl6 l-(4-Fluorophenyl)-1-propanone,... 

A mixture of 2.3 parts of 2-(4-methoxyphenyl)ethyl methanesulfonate, 4.9 parts of l-[(4-fluorophenyl)methyl]-N-(4-piperidinyl)-lH-benzimidazol-2-amine dihydrobromide, 3.2 parts of sodium carbonate, 0.1 part of potassium iodide and 90 parts of N,N-dimethylformamide is stirred overnight at 70°C. The reaction mixture is poured onto water. The product is extracted with methylbenzene. The extract is washed with water, dried, filtered and evaporated. The residue is purified by column-chromatography over silica gel using a mixture of trichloromethane and methanol (98 2 by volume) as eluent. The pure fractions are collected and the eluent is evaporated. The residue is crystallized from 2,2 -oxybispropane, yielding 2.2 parts (48%) of 1-(4-fluorophenylmethyl)-N-[l-[2-(4-methoxyphenyl)ethyl]-4-piperidinyl]-lH-benzimidazol-2-amine MP 149.1°C. 

Chemical Name 2H-l,2,4-Benzothiadiazine-7-sulfonamide, 3,4-dihydro-6-chloro-3-((4-fluorophenyl) methyl)-, 1,1-dioxide... 

Thieno[3,4-d]pyrimidines with a 4-(4-fluorobenzoyl)piperidine or bis(4-fluorophenyl)methyl-4-piperylidene substituent instead of the 4-phenyl-substituted piperazine group in compounds 306 were twenty times more potent as selective 5-HT2 antagonists than ketanserin (91MI1). 

The title compound, l-[bis-(4-fluorophenyl)methyl]-4-(3-phenylpropenyl) piperazine, 123, clinically used as a calcium channel blocker of the piperazine class166, has been labelled with 18F by alkylation of Af-cinnamylpiperazine with 4-[18F]fluoro-4 -fluoroben-zhydryl chloride 124 (equation 73)167. The biodistribution of 123, its effect on the dopamine reuptake blockers and metabolic products are under investigation167. 

This centrally acting analgesic agent242, ethyl 2-amino 6 [(4-fluorophenyl)methyl] amino -3-pyridinyl-2,6-14C carbamate maleate, 238, has been 14C-labelled243 in nine steps starting with potassium cyanide[14C] and 1,3-dibromopropane (equation 100). 

---