4- nitrotoluene, fluorination

Cas/liquid reaction 2 [CL 2] Direct fluorination of 4-nitrotoluene using elemental fluorine... 

Reductive oxidation of />-nitrotoluene to -aminobenzaldehyde, 31, 6 Reformatsky reaction, 37, 38 Reissert s compound, 38, 58 Reissert reaction, 38, 58 Replacement, benzenesulfonate groups by bromine atoms, 31, 82 bromine, by a thiol group, 30, 35 by fluorine, 36, 40 chlorine, by an amino group, 31,45 by a thiol group, 32, 101 by iodine, 30, 11 by methoxyl, 32, 79 by nitrile, 36, 50 in an imido-chloride group by an anilino group, 31, 48 chlorine and nitro by ethoxyl radicals, 32,68... 

Selective fluorination of 4-nitrotoluene, 1,3-dicarbonyl, and heterocyclic compounds [76]... 

Direct fluorination of toluene and nitrotoluene Falling film and bubble column MSR Jahnisch et al. [30]... 

The fluorination reaction of p-nitrotoluene in formic acid can be carried out using 10% F2 in N2 in a three-channel microreactor to give fluorinated product in 78% yield (Table 8.3) [4,5,6]. Fluorination of 4-nitrotoluene is carried out in mixtures of acetonitrile and formic acid (3 2 v/v) because the formation of fluorinated p-nitrotoluene leads to blockage of the microchannel due to the low solubility of the substrate in formic acid. 

Selective fluorination of 4-nitrotoluene, 1,3-dicarbonyl, and heterocyclic compounds [46] Chlorination of acetic acid [47] Photochlorination of toluene 2,4-diisocyanate (TDI) [48]... 

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