Fluorescence sensors BAPTA

The structure of the fluorescent sensor Fluo-3 consists of BAPTA attached to a xanthene derivative as the fluorophore (Fig. 18.2). Many xanthene-based (sometimes referred to fluorescein-based) fluorescent sensors such as Fluo-3 have been reported. These compounds have an aromatic moiety that recognizes or reacts with the target at the 9-position of the xanthene ring. 

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