Fluonnated anesthetics

Dozens of compounds have been used in in vivo fluonne NMR and MRI studies, chosen more for their commercial availability and established biochemistry than for ease of fluonne signal detection [244] Among the more common of these are halothane and other fluonnated anesthetics [245, 246], fluorodeoxyglucose [242 243], and perfluonnated synthetic blood substitutes, such as Fluosol [246], a mixture of perfluorotnpropylamine and perfluorodecahn Results have been limited by chemical shift effects (multiple signals spread over a wide spectral range) and long acquisition times... 

F-Labeled Radiopharmaceuticals D F Halpern Fluonnated Anesthetics L L Ferstandig... 

Desflurane can be made by fluonnation of isoflurane with potassium fluonde [/J] or with bromine tnfluonde [14] (equation 2) Although approximately six times more desflurane than isoflurane is required for anesthesia, it achieves the anesthetic state and the patient recovers from this state more rapidly This feature seems to be of interest to some anesthesiologists One negative property is that it irritates the breathmg passageway, especially in children Desflurane is flammable at higher levels of anesthetic use It is the least metabolized of all the commercial anesthetics, producing tnfluoroacetic acid and fluonde ion [75]... 

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