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Fluconazole selective toxicity

FLUCONAZOLE, ITRACONAZOLE, KETOCONAZOLE, VORICONAZOLE (POSSIBLY POSACONAZOLE) VINCA ALKALOIDS -VINBLASTINE, VINCRISTINE, VINORELBINE t adverse effects of vinblastine and vincristine Inhibition of CYP3A4-mediated metabolism. Also inhibition of P-gp efflux of vinblastine Monitor FBCs and watch for early features of toxicity (pain, numbness, tingling in the fingers and toes, jaw pain, abdominal pain, constipation, ileus). Consider selecting an alternative drug... [Pg.566]

A rabbit model study suggested that topical 0.2% fluconazole has pharmacokinetic properties, low toxicity, and selective MICs that merit further studies as an ophthalmic agent (Yee et al.). [Pg.210]


See other pages where Fluconazole selective toxicity is mentioned: [Pg.419]    [Pg.345]    [Pg.1218]    [Pg.107]    [Pg.342]    [Pg.98]    [Pg.182]    [Pg.263]    [Pg.328]   
See also in sourсe #XX -- [ Pg.5 , Pg.268 ]




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