Flexible dosage schedules

In a second double-blind, placebo-controlled trial with polysomnographic control, 98 patients underwent a 2-week single-blind treatment period with placebo, and 58 of these were then randomized to pregabalin or placebo for 12 weeks using a flexible dosage schedule [252 ]. Unsteadiness and daytime sleepiness were common with pregabalin the intensity was mild at... 

The insulin dosage pattern tliat most closely follows nonnal insulin production is a multiple-dose plan sometimes called intensive insulin therapy. In tins r men, a single dose of intennediate- or long-acting insulin is taken in tlie morning or at bedtima Small doses of regular insulin are taken before meals based on tlie patient s blood ucose levels. This allows for greater flexibility in tlie patient s life-style, but can also be an inconvenience to tlie patient (eg, tlie need to always have supplies witli tliem, tlie lack of privacy, inconvenient schedules). 

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