Flavothebaone derivatives

Further rearrangements of the Diels-Alder adducts of thebaine and their derivatives have been studied. Thebainequinol and one of its methyl ethers are rearranged to flavothebaone derivatives by alkalis. The reaction is analogous... 

No crystalline product is obtained when flavothebaone is oxidized with hydrogen peroxide, ozone, or other reagents. The trimethyl ether can be converted to a N-oxide on oxidation with perbenzoic acid the N-oxide is reduced to the parent base by sulphurous acid. The trimethyl ether can be brominated to a dibromo-derivative [2],... 

The Beckmann transformation of flavothebaone trimethyl ether oxime yields an isoxime containing four methoxyl groups, which on treatment with methanol and hydrochloric acid yields a substance yrith one additional methoxyl. Both the isoxime and the methyl-derivative remain unchanged on heating with methanolic potassium hydroxide for seven hours [2],... 

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