Flavonoid mutants

Another area in which Arabidopsis genetics is proving to be useful is the study of the proposed role of flavonoids in regulating auxin transport. Several years ago, Jacobs and Rubery published the first evidence that flavonoids could specifically compete with naphthylphthalamic acid for binding to the auxin efflux carrier in etiolated zucchini hypocotyls.35 This finding was somewhat controversial, however, and no additional evidence for the connection between flavonoids and auxin transport was reported for some time. Brown et al. have now used Arabidopsis flavonoid mutants to generate new evidence in support of a role for flavonoids in the regulation of polar auxin movement.6 These experiments took... 

DONG, X., BRAUN, E.L., GROTEWOLD, E., Functional conservation of plant secondary metabolic enzymes revealed by complementation of Arabidopsis flavonoid mutants with maize genes, Plant Physiol., 2001,127,46-57. 

HV032 Reuber, S., B. Jende-Strid, V. Wray, and G. Weissenbock. Accumulation of the chalcone isosalipurposide in pri- HV042 mary leaves of barley flavonoid mutants indicates a defective chalcone isomerase. Physiol Plant 1997 101(4) ... 

Reuber, S., Bornman, J.F., and Weissenbock, G., A flavonoid mutant of barley (Hordeum vulgare L.) exhibits increased sensitivity to LTV-B radiation in the primary leaf, Plant Cell Environ., 19, 593, 1996. 

Li J, Ou-Lee T-M, Raba R, Amundson RG, Last RL. 1993. Arabidopsis flavonoid mutants are hypersensitive to UY-B irradiation. Plant Cell 5 171-179. 

Peer WA, Bandyopadhyay A, Blakeslee JJ, Makam SN, Chen RJ, Masson PH, Murphy AS. 2004. Variation in expression and protein localization of the PIN family of auxin efflux facilitator proteins in flavonoids mutants with altered auxin transport in Arabidopsis thaliana. Plant Cell 16 1898-1911. 

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