Field squid axon membranes, effects

A model, based on a perturbation analysis of the highly successful empirical formulation of Hodgkin and Huxley (1), has been developed which makes predictions of the effect of oscillating fields on a particular nerve membrane system (2). In the present paper, a theoretical model will be presented along with some of the predicted effects of AC electric fields on the Hodgkin-Huxley (HH) model of squid axon membranes. 

An approach somewhat analogous to that of Barnes and Hu was adopted by Pickard and Rosenbaum.They examined the effects of an impressed radiofrequency field on the resting potential across the plasma membrane and the effects of such fields with regard to ion transit time within an ion channel spanning the membrane. Of interest is their conclusion that the frequency range at which transit time effects are no longer important lies well below the microwave portion of the spectrum. This estimate was based upon data for the sodium ion current in the squid axon membrane. 

S. Ohki, Membrane Potential of Squid Axons Comparison between the Goldman-Hodgkin-Katz Equation and the Diffusion/Surface Potential Equation, in Charge and Field Effects in Biosystems (M. J. Allen and P. N. R. Usherwood, eds.), pp. 147-156, Abacus Press, Tunbridge Wells (1984). 

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