Fibre optics photochemical

Lemmer K, Donoso Mantke O, Bae HG, Groen J, Drosten C, Niedrig M (2004) External quality control assessment in PCR diagnostics of dengue virus infections. J Clin Virol 30(4) 291-296 Leshem B, Sarfati G, Novoa A, Breslav I, Marks RS (2004) Photochemical attachment of biomolecules onto fibre-optics for construction of a chemiluminescent immunosensor. Luminescence 19(2) 69-77... 

The collimated optics of the set-up demonstrated can be substituted by fibre cities. This type of equipment is shown in Fig. 4.11 using a bifurcated fibre and a diode array. Under these conditions white light has to be used to produce a reflection spectrum monitored by the diode array. However, white light causes undefined photochemical conditions. For this reason a third fibre arm is used, which guides monochromatic radiation to the sample. If the white radiation is blocked by a shutter, it may not disturb the monochromatic photoirradiation. Since modem diode arrays take spectra within a few milliseconds the time of measurement stays short compared to the total photochemical process time. This type of equipment can be used to monitor the photoprocess during irradiation of photoresists [101]. 

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