Ferrichrome colicin

Synonym with fhuA. A mutation (T-one) in the outer membrane protein which serves as the receptor for ferrichrome, colicin M, and phages Tl, T5, and 80 A defect in the gene encoding pilin... 

Mainly the outer membrane ferrichrome receptor and transporter FhuA will be discussed because most structural and functional studies have been performed with this protein. In fact, FhuA was the first outer membrane protein identified (called TonA), with known functions as a phage and colicin receptor, that are related to iron transport (for a historical account, see Braun and Hantke 1977). 

Figure 10. Diagrammatic sketch of the competition between phage colicin and siderophore for the outer membrane receptor in the enteric bacteria. (A) Escherichia coli K-12. (1) Ferrichrome receptor phage = TI, T5, 80 colicin = M siderophore = ferrichrome. (2) Ferric en-terobactin receptor phage = colicin = B siderophore = ferric entero-bactin. (B) Salmonella typhimurium LT-2. (1) Ferrichrome receptor ...

Thus, S. typhimurium appears to have a common surface receptor for ferrichrome, albomycin, and ES18 phages which is the genetic equivalent of the ferrichrome-Tl, T5, 80-colicin M receptor in E. coli. 

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