Ferf-Butylamine

Amines Methylamine Dimethylamine Ethylamine Diethylamine Propylamine Dipropylamine Isopropylamine Diisopropylamine Butylamine ferf-Butylamine Allyl amine Cyclohexylamine... 

Yield of the a,p unsaturated ketone after elimination of ferf-butylamine. 

II, and III), two were monohydrates (termed a-monohydrate and /3-monohydrate) and one was a ferf-butylamine disolvate. The differences in the powder patterns of the phases were readily evident (Table 1). This study demonstrates the unique ability of x-ray diffractometry for the identification of (1) anhydrous compound existing in both crystalline and amorphous states, (2) different polymorphic forms of the anhydrate, (3) the existence of solvates where the solvent of crystallization is water (hydrate) or an organic solvent (in this case, /m-butylamine), and (4) polymorphism in the hydrate. 

Aliphatic nitro compounds with the nitro group on a tertiary carbon were reduced to amines with aluminum amalgam [146 or iron [559]. 2-Nitro-2-methylpropane afforded ferf-butylamine in 65-75% yield [146. Even some secondary nitroalkanes were hydrogenated to amines. fra s-l,4-Dinitrocy-clohexane was converted to frans-l,4-diaminocyclohexane with retention of configuration. This may be considered as an evidence that the intermediate nitroso compound is reduced directly and not after tautomerization to the isonitroso compound [560] (see Scheme 54). 

Thus ferf-butylamine as an incoming nucleophile directs the formation of geminal products, while ethylamine favors nongeminal products. 

The feasibility of acid-catalyzed direct hydroamination has been demonstrated. Acidic zeolites afford, at low conversions, highly selective formation of ethyla-mine,297,298 isopropylamine,298 and ferf-butylamine,298-301 in the reaction of ammonia with ethylene, propylene, and isobutylene, respectively. Amine formation is explained as a reaction of surface carbocation intermediates with adsorbed or... 

C4HmN 109-73-9) see Bamethan Buclosamide Butanilicainc, Carbutamide Parsalmide Tybamate ferf-butylamine... 

Method B. cWV-rerf-ButyUysergamide Maleate (lb). A refluxing slurry of 3.15 g of d-lysergic acid in 150 ml of CHCls was treated with 7.1 g (96 mmol) of ferf-butylamine in 25 ml of CHCls and 2 ml of POCh which were added simultaneously from separate dropping funnels over 2-3 min. The reaction mixture was kept at reflux for another 3-5 min until a clear, amber solution resulted. The solution was cooled to room temperature and worked up in the same manner as described above giving 2 g of lb. The reactants were scaled up eight times for the preparation of le. 

One of the difficulties encountered when investigating or discussing rotation barriers about C-0 and especially C-N bonds is that this process may be overshadowed by a competitive process, namely inversion. Inversion barriers for simple amines are in the region of 5 kcal/mol [86], thus somewhat above the rotation barrier reported in Table 7 for methylamine. However, bulky substituents may markedly increase the rotation barrier and cause inversion to become the preferred process of conformational interconversion. This is precisely what happens with ferf-butylamines, where inversion (LXXVa-LXXVb interconversion) but not C-N bond rotation (LXXVa-LXXVc interconversion) is observed [87],... 

The best evidence for a CT process rather than direct hydrogen abstraction involves the values of kT s-butyl- and ferf-butylamine display much the same value 156> triethylamine and ferf-butyldimethylamine are equally reactive and some 50 times more so than primary amines 155>. Thus the rate constant for reaction is independent not only of the type of C—H bond a to the nitrogen but also of the presence or absence of a-hydrogens. Such evidence demands that abstraction of an a-hydrogen not be involved in the rate-determining quenching reaction. Moreover, the relative reactivity of amines (tertiary > secondary > primary) is proportional to the ease with which they are oxidized. 

Fig. 10. The influence of primary amines on the oxidation of acetaldehyde at 124 C [69, 71]. Acetaldehyde pressure 100 torr oxygen pressure 100 torr. (a) No amine added (b) 0.95 torr methylamine (c) 1.79 torr ethylamine (d) 2.27 torr n-butyl-amine (e) 2.56 torr ferf-butylamine (f) 2.22 torr iso-propylamine.

Transamination reactions. Most of the known imidotin cubanes of the type [Sn( a3-NR)]4 have been prepared via transamination reactions between a tin amide reagent and a primary amine. The first example was reported by Veith in 1979 and involved the reaction of the cyclic diazastannylene 1 (Scheme 2.2.2) with ferf-butylamine at 50 °C. However, the initial reaction of these reagents produces either the tricyelic compound 2 or the yeco-cubane 3, depending on the reaction stoichiometry (from molar ratios of lifBuNHa of 2 1 or 3 4, respectively). Compounds 2 and 3 are converted to the cubane... 

Polymerization of MMA in the presence of paramagnetic rathenium complexes is of special interest. Amine free polymerization proceeded slowly and stopped at low conversion. For example, maximum conversion of MMA catalyzed by 5 was nearly 40% in 200 hours. Introduction of ferf-butylamine into the polymerization mixture led to fast polymerization (nearly 100% in two... 

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