Fast dispersible tablets

During the last years fast dispersible tablets for the disintegration in the mouth were developed and commercialized e.g. Flash tabs . First of all this applies to analgesic drugs. For this kind of tablets the superdisintegrants like crospovidone are used to obtain a disintegration within less than one minute. A typical example is ibuprofen [654,655]. 

Table 1 Oral Fast-Dispersing Tablet Technologies...

Schiermeier S, Schmidt PC. Fast dispersible ibuprofen tablets. Eur] Pharm Sci 2002 15(3) 295-305. 

FAST-DISPERSING, FAST-DISSOLVING, OR FAST-MELTING TABLETS... 

A. Fini, et al.. Fast dispersible/slow relejising ibuprofen tablets. Eur. J. Pharm. Biopharm., 69(1), 335-341,2008. 

Uses Builder, sequestrant, detergent, dispersant in automatic-dish washing detergents, laundry detergent powds. and tablets Features High absorption capacity very fast dissolution in water Properties Wh. granulated powd. particle size 10% max rejected on 1.00 mm. 40% min. rejected on 0.250 mm. 75% rejected on 0.160 mm bulk dens. 0.35-0.55 kg/l pH (1% sol.) 9.2 desiccation loss 150 C 1.5%... 

Uses Builder, sequestrant, detergent, dispersant in automatic-dish washing detergents, laundry detergent powds. and tablets Features Very fast hydration in water... 

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