Factors Controlling the Efficiency of a Catalytic Reaction

When the successive steps of a catalytic cycle are examined independently from each other, they have their own reaction rate. But when they are involved in a catalytic cycle, the effective rates of the successive steps are not independent from each other. Indeed, the rate of step i is v, = where ki is the rate constant of step i, R, is the reagent 

4 Mechanism of the Mizoroki-Heck Reaction when the Catalytic Precursor is Pd(OAc)2 Associated with Bisphosphine Ligands 

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