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Facial Dyskinesia from the Antihistamines

It seems probable that the anticholinergic activity of antihistamine agents centrally alter nigrostriatal cholinergic-dopaminergic interaction and thereby produce acute and chronic oral dyskinesia. In patients with markedly severe acute dystonia induced by antihistamines, an intramuscular or intravenous trial of the centrally active cholinomimetic, physostigmine, might prove therapeutic. [Pg.389]

Angelini G, Meneghini CL (1977) Dermatitis in engineers due to synthetic coolants. Contact Dermatitis 3 219-220 [Pg.389]

Brait KA, Zagerman AJ (1977) Dyskinesias after antihistamine use. N Engl J Med 296 111-114 [Pg.389]

Burry JN (1978) Ethylenediamine sensitivity with a systemic reaction to piperazine citrate. Contact Dermatitis 4 380 [Pg.389]

Cahn MM, Levy EJ (1957) Ultraviolet light factor in chlorpromazine dermatitis. Arch Dermatol 75 38-40 [Pg.389]


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