F 4-Bromo-l -butene

Allyl 4-toluenesulfonate, 3315 f Allyl vinyl ether, 1904 f 3-Aminopropene, 1254 3-Azidopropene, 1188 f l-Bromo-2-butene, 1548 f 3-Bromo-l-propene, 1153 /V-Chloroallylaminc. 1202 l-Chloro-4-(2-nitrophenyl)-2-butene, 3270 f 3-Chloropropene, 1158 f 3-Cyanopropene, 1465 f Diallylamine, 2450 f Diallyl ether, 2431... 

Allyloxy-2,3-epoxypropane, 2428 iV-Allylthiourea, 1595 f 3-Aminopropene, 1250 3-Azidopropene, 1184 f 3-Bromo-l-propene, 1149 f l-Bromo-2-butene, 1543... 

Of the lower members of this reactive group of compounds, the more lightly substituted are of high flammability and many are classed as peroxidisable and as polymerisable compounds. Individually indexed compounds are f Acrylonitrile, 1104 f 4-Bromo-l-butene, 1544 f 3-Bromo-l-propene, 1149 f l-Bromo-2-butene, 1543 4-Bromocyclopentene, 1878 f Bromoethylene, 0723 f Bromotrifluoroethylene, 0576 f 2-Chloro-1,3-butadiene, 1447 f 3-Chloro-l-butene, 1547... 

Chen, Q, Qiu, X-L. and Qing, F-L. (2006) Indium-mediated diastereoselective allylation of D- and L-glyceraldimines with 4-bromo-l,l,l-trifluoro-2-butene Highly stereoselective synthesis of 4,4,4-trifluoroisoleucines and 4,4,4-trifluorovaline. J. Org. Chem., 71, 2162-2161. 

The anti addition of diethyl 7V,Ar-dibromophosphoramidates to acyclic and cyclic alkenes was achieved in the presence of boron trifluoride, which makes the ionic dissociation of the N —Br bond more labile94,9s. After reduction of the initial /J,lV-dibromo adducts with sodium bisulfite, the /i-bromo-A -hydrophosphoramides 3 precursor of / -bromo amine hydrochlorides 4 were obtained (Table 4). However, a mixture of diastereomers was obtained from (Z)-l-phenyl-l-propene and (E)- and (Z)-l,2-diphenylethylene. Direct assignment of stereochemistry by H NMR of the phosphoroamidates derived from 2-butenes was not possible. Detailed analysis is, however, possible for the H-NMR spectra of the /J-bromo amine hydrochlorides. As determined by 31P NMR spectroscopy all additions to unsymmetrical aliphatic alkenes were not regiospecific. The /f-bromo amine hydrochlorides were converted to 1,2-diamines95. 

This selective metalation has been used for the synthesis of several bisabolane sesquiterpenes. Thus the sesquiterpene (- )-/f-bisabolene (7) can be synthesized in one step from metalated (-)-limonene by reaction with l-bromo-3-methyl-2-butene. Two... 

Butene l-(2-Bromo-anilino)-3-oxo-4.4.4-lrifluoro- E10b2, 234 f. (Educt)... 

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