Big Chemical Encyclopedia

Chemical substances, components, reactions, process design ...

Articles Figures Tables About

Extracolumn band broadening injector

As shown in Figure 3.8, an increased injection volume can have a negative effect on the column efficiency. Therefore, the injection volume should be appropriately scaled down when an HPLC method is transferred to a UHPLC method or vice versa to achieve the same sensitivity and avoid overloading or detector saturation and extracolumn band-broadening. The scaling factor is mainly based on column dimension, as shown in Eq. (3.26). However, lower injection volumes than calculated can often be used on UHPLC to achieve the same sensitivity due to enhanced peak heights from use of the high-resolution columns and low carryover from the injector ... [Pg.85]

See other pages where Extracolumn band broadening injector is mentioned: [Pg.279]    [Pg.104]    [Pg.45]    [Pg.45]    [Pg.433]    [Pg.90]    [Pg.238]    [Pg.471]    [Pg.1438]    [Pg.1043]    [Pg.1291]    [Pg.1366]    [Pg.89]   
See also in sourсe #XX -- [ Pg.45 ]



SEARCH



Band broadening

Extracolumn band broadening

Injector

© 2024 chempedia.info