Extracellular space ligand concentration

Fig. 6.7 Paths for increase and reduction of cytosolic Ca2+concentration. Influx of Ca2+ from the extracellular space takes place via Ca2+channels the open state ofthese is controlled by binding of ligand L or by a change in the membrane potential (V). According to the type of ion channel, the ligand may bind from the cytosolic or the extracellular side to the ion channel protein. The entering Ca2+binds to...

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